"It seems like this past week has been quite challenging for you," a disembodied voice tells me, before proceeding to ask a series of increasingly personal questions. "Have you been feeling down or depressed?" "Can you describe what this feeling has been like for you?" "Does the feeling lift at all when something good happens?" When I respond to each one, my chatbot interviewer thanks me for my honesty and empathises with any issues. By the end of the conversation, I will have also spoken about my sleep patterns, sex drive and appetite for food.

Children diagnosed with anxiety disorders are taught a range of strategies to navigate situations of heightened anxiety. Techniques such as deep breathing and repetition of mantras are commonly employed, as they are known to be calming and reduce elevated heart rates. Although these strategies are often effective, their successful application relies on prior training of the children for successful use when faced with challenging situations. This paper investigates a pocket-sized companion robot designed to offer a relaxation technique requiring no prior training, with a focus on immediate impact on the user's heart rate. The robot utilizes a tactile game to divert the user's attention, thereby promoting relaxation. We conducted two studies with children who were not diagnosed with anxiety: a 14-day pilot study with two children (age 8) and a main study with 18 children (ages 7-8). Both studies employed a within-subjects design and focused on measuring heart rate during tactile interaction with the robot and during non-use. Interacting with the robot was found to significantly lower the study participants' heart rate (p$<$0.01) compared to the non-use condition, indicating a consistent calming effect across all participants. These results suggest that tactile companion robots have the potential to enhance the therapeutic value of relaxation techniques.

The classification of clinical notes into specific diagnostic categories is critical in healthcare, especially for mental health conditions like Anxiety and Adjustment Disorder. In this study, we compare the performance of various Artificial Intelligence models, including both traditional Machine Learning approaches (Random Forest, Support Vector Machine, K-nearest neighbors, Decision Tree, and eXtreme Gradient Boost) and Deep Learning models (DistilBERT and SciBERT), to classify clinical notes into these two diagnoses. Additionally, we implemented three oversampling strategies: No Oversampling, Random Oversampling, and Synthetic Minority Oversampling Technique (SMOTE), to assess their impact on model performance. Hyperparameter tuning was also applied to optimize model accuracy. Our results indicate that oversampling techniques had minimal impact on model performance overall. The only exception was SMOTE, which showed a positive effect specifically with BERT-based models. However, hyperparameter optimization significantly improved accuracy across the models, enhancing their ability to generalize and perform on the dataset. The Decision Tree and eXtreme Gradient Boost models achieved the highest accuracy among machine learning approaches, both reaching 96%, while the DistilBERT and SciBERT models also attained 96% accuracy in the deep learning category. These findings underscore the importance of hyperparameter tuning in maximizing model performance. This study contributes to the ongoing research on AI-assisted diagnostic tools in mental health by providing insights into the efficacy of different model architectures and data balancing methods.

This study integrates causal inference, graph analysis, temporal complexity measures, and machine learning to examine whether individual symptom trajectories can reveal meaningful diagnostic patterns. Testing on a longitudinal dataset of N=45 individuals affected by General Anxiety Disorder (GAD) and/or Major Depressive Disorder (MDD) derived from Fisher et al. 2017, we propose a novel pipeline for the analysis of the temporal dynamics of psychopathological symptoms. First, we employ the PCMCI+ algorithm with nonparametric independence test to determine the causal network of nonlinear dependencies between symptoms in individuals with different mental disorders. We found that the PCMCI+ effectively highlights the individual peculiarities of each symptom network, which could be leveraged towards personalized therapies. At the same time, aggregating the networks by diagnosis sheds light to disorder-specific causal mechanisms, in agreement with previous psychopathological literature. Then, we enrich the dataset by computing complexity-based measures (e.g. entropy, fractal dimension, recurrence) from the symptom time series, and feed it to a suitably selected machine learning algorithm to aid the diagnosis of each individual. The new dataset yields 91% accuracy in the classification of the symptom dynamics, proving to be an effective diagnostic support tool. Overall, these findings highlight how integrating causal modeling and temporal complexity can enhance diagnostic differentiation, offering a principled, data-driven foundation for both personalized assessment in clinical psychology and structural advances in psychological research.

Personalized therapy, in which a therapeutic practice is adapted to an individual patient, can lead to improved health outcomes. Typically, this is accomplished by relying on a therapist's training and intuition along with feedback from a patient. However, this requires the therapist to become an expert on any technological components, such as in the case of Virtual Reality Exposure Therapy (VRET). While there exist approaches to automatically adapt therapeutic content to a patient, they generally rely on hand-authored, pre-defined rules, which may not generalize to all individuals. In this paper, we propose an approach to automatically adapt therapeutic content to patients based on physiological measures. We implement our approach in the context of virtual reality arachnophobia exposure therapy, and rely on experience-driven procedural content generation via reinforcement learning (ED-PCGRL) to generate virtual spiders to match an individual patient. Through a human subject study, we demonstrate that our system significantly outperforms a more common rules-based method, highlighting its potential for enhancing personalized therapeutic interventions.

A common denominator for most therapy treatments for children who suffer from an anxiety disorder is daily practice routines to learn techniques needed to overcome anxiety. However, applying those techniques while experiencing anxiety can be highly challenging. This paper presents the design, implementation, and pilot study of a tactile hand-held pocket robot AffectaPocket, designed to work alongside therapy as a focus object to facilitate coping during an anxiety attack. The robot does not require daily practice to be used, has a small form factor, and has been designed for children 7 to 12 years old. The pocket robot works by sensing when it is being held and attempts to shift the child's focus by presenting them with a simple three-note rhythm-matching game. We conducted a pilot study of the pocket robot involving four children aged 7 to 10 years, and then a main study with 18 children aged 6 to 8 years; neither study involved children with anxiety. Both studies aimed to assess the reliability of the robot's sensor configuration, its design, and the effectiveness of the user tutorial. The results indicate that the morphology and sensor setup performed adequately and the tutorial process enabled the children to use the robot with little practice. This work demonstrates that the presented pocket robot could represent a step toward developing low-cost accessible technologies to help children suffering from anxiety disorders.

Depressive and anxiety disorders are widespread, necessitating timely identification and management. Recent advances in Large Language Models (LLMs) offer potential solutions, yet high costs and ethical concerns about training data remain challenges. This paper introduces a pipeline for synthesizing clinical interviews, resulting in 1,157 interactive dialogues (PsyInterview), and presents EmoScan, an LLM-based emotional disorder screening system. EmoScan distinguishes between coarse (e.g., anxiety or depressive disorders) and fine disorders (e.g., major depressive disorders) and conducts high-quality interviews. Evaluations showed that EmoScan exceeded the performance of base models and other LLMs like GPT-4 in screening emotional disorders (F1-score=0.7467). It also delivers superior explanations (BERTScore=0.9408) and demonstrates robust generalizability (F1-score of 0.67 on an external dataset). Furthermore, EmoScan outperforms baselines in interviewing skills, as validated by automated ratings and human evaluations. This work highlights the importance of scalable data-generative pipelines for developing effective mental health LLM tools.

Anxiety is endemic to every person, with an occurrence rate of approximately 20% [World Health Organization, 2017]. Between 2020 and 2022, over one in six people (17.2% or 3.4 million people) aged 16 to 85 years experienced an anxiety disorder [Australian Bureau of Statistics]. Anxiety is caused by changes in the situation, nervousness and common symptoms, including sweating, trembling and excessive worrying, which affect a person's daily life. Anxiety disorders encompass a range of conditions, such as generalised anxiety disorder (GAD), panic disorder (PD), social anxiety disorder (SAD), obsessive-compulsive disorder (OCD), various phobia-related disorders, physical pain related protective behaviour [Li et al., 2020, 2021] and depression [Ghosh and Anwar, 2021]. Current clinical approaches for diagnosing these disorders often suffer from limitations in accuracy and objectivity, relying heavily on self-reports, patient histories and clinical observations. These methods can be subjective and may not capture the nuanced neural and behavioural patterns associated with anxiety, leading to potential misdiagnoses. Recent research has shown promising results in using machine learning techniques to detect anxiety through physiological analysis [Abd-Alrazaq et al., 2023], such as respiration, electrocardiogram (ECG), photoplethysmography (PPG), electrodermal response (EDA) and electroencephalography (EEG), to identify patterns associated with anxiety states [Abd-Alrazaq et al., 2023].

This paper describes our participation in Task 3 and Task 5 of the #SMM4H (Social Media Mining for Health) 2024 Workshop, explicitly targeting the classification challenges within tweet data. Task 3 is a multi-class classification task centered on tweets discussing the impact of outdoor environments on symptoms of social anxiety. Task 5 involves a binary classification task focusing on tweets reporting medical disorders in children. We applied transfer learning from pre-trained encoder-decoder models such as BART-base and T5-small to identify the labels of a set of given tweets. We also presented some data augmentation methods to see their impact on the model performance. Finally, the systems obtained the best F1 score of 0.627 in Task 3 and the best F1 score of 0.841 in Task 5.

The copilot framework, which aims to enhance and tailor large language models (LLMs) for specific complex tasks without requiring fine-tuning, is gaining increasing attention from the community. In this paper, we introduce the construction of a Healthcare Copilot designed for medical consultation. The proposed Healthcare Copilot comprises three main components: 1) the Dialogue component, responsible for effective and safe patient interactions; 2) the Memory component, storing both current conversation data and historical patient information; and 3) the Processing component, summarizing the entire dialogue and generating reports. To evaluate the proposed Healthcare Copilot, we implement an auto-evaluation scheme using ChatGPT for two roles: as a virtual patient engaging in dialogue with the copilot, and as an evaluator to assess the quality of the dialogue. Extensive results demonstrate that the proposed Healthcare Copilot significantly enhances the capabilities of general LLMs for medical consultations in terms of inquiry capability, conversational fluency, response accuracy, and safety. Furthermore, we conduct ablation studies to highlight the contribution of each individual module in the Healthcare Copilot. Code will be made publicly available on GitHub.